Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject.
Broadly neutralizing antibodies are considered an important part of a successful HIV vaccine.A better understanding of the factors underlying their development during infection and of the epitopes they target is needed to elicit similar antibody Cosmetic Bag responses by vaccination.We and others reported that, on average, it takes 2 to 3 years for